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Questions of medicine and science formed half way ‘round the world

My path to a career in science and medicine was convoluted, but not without direction. I grew up in east Africa on an island in the Indian Ocean. Both my maternal grandparents died at very young ages of undiagnosed conditions. While the setting was idyllic, the reason for my grandparents’ deaths, or rather the lack of a reason bothered me.

This great gap in understanding—the causes of...

Research leads to increased options for cancer treatment

In my previous post I shared how we have learned so much about endometrial cancer by analyzing the molecular features of the tumours.

Recently, we have been really excited in showing that these molecular features can be determined on endometrial samples, and do not require analysis of the whole uterine specimen, such as from a hysterectomy. 

Most women diagnosed with...

Treating Endometrial Cancer in Young Women

We know that around 15% of endometrial cancers occur in women less than 50 years of age, and 5% in women less than 40. These women may not yet have had a family and likely have not entered menopause. Thus they may not be ready to have their uterus and ovaries removed, which is the usual surgical step when endometrial cancer is diagnosed. 

It is very challenging to advise these women as...

Endometrial Cancer: How Molecular Testing Can Improve Treatment Strategies for Women

Hello again and thanks for tuning in! Today I am going to share some recent work we have been doing in endometrial cancer or cancer of the ‘womb.’ This is the most common cancer in women in the developed world yet it is surprisingly understudied.  More than any other cancer I treat there is profound inconsistency in how pathologists, surgeons, medical and radiation oncologists manage this...

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