Researchers discover how a chromosomal deletion may lead to bone marrow failure or leukemia

Researchers identified that a loss of either one of two micro-RNAs (a type of molecule, similar to DNA) can lead to a type of pre-leukemia called MDS, a bone marrow disorder caused by genetic changes in blood stem cells. Thirty to 40 per cent of patients with MDS may later develop acute myeloid leukemia, an aggressive blood cancer.